Diabetes is not terrible, what is terrible is the complication, and if the blood sugar is not controlled well, and if it is complicated with hypertension, hyperlipidemia will easily lead to complications, and diabetic nephropathy is also a relatively serious disease. Diabetic patients need to pay special attention to it. To control blood pressure to prevent complications.
Genetic factors: It is also a common cause of diabetic nephropathy. People with kidney disease in most diabetic families are also prone to develop kidney disease after developing diabetes. The difference in the glut1 menu and regulation of Mesangial cells among different inpiduals can also lead to kidney damage. Therefore, we should strengthen monitoring and prevention!
Renal hemodynamic abnormalities: The main cause of diabetic nephropathy is the manifestation of abnormal renal hemodynamics. Renal hemodynamic abnormalities mentioned here include: glomerular basement membrane type IV collagen messenger sugar nucleic acid increased; increased pressure; the impact of hyperglycemia.
Hyperglycemia damage: Studies have shown that hyperglycemia is closely associated with the development of diabetic nephropathy. If the patient's blood glucose control is poor, it may accelerate the development of the disease; in contrast, good glycemic control will significantly reduce and delay the disease's progression.
The impact of hypertension: Although there is no direct correlation between the occurrence of diabetic nephropathy and hypertension, it can accelerate the progression of diabetic nephropathy from the time of microalbuminuria to the stage of microalbuminuria or the increase of blood pressure of hypertension. Further deterioration of renal function exacerbates urinary albumin excretion in patients. Therefore, people with diabetes must control their blood pressure and prevent the occurrence of kidney disease more scientifically!
The most obvious symptom of diabetic nephropathy is proteinuria. There is no clinical proteinuria in early diabetic nephropathy of proteinuria, and only a radioimmunoassay can be used to detect microalbuminuria. The only early manifestation of diabetic nephropathy is proteinuria, which gradually develops from intermittent to persistent.
Edema is also a common symptom of diabetic nephropathy. Edema clinical diabetic nephropathy early generally no edema, a few patients before the reduction of plasma protein, may have mild edema. If a large number of proteinuria, plasma protein is low, edema aggravated, mostly disease progression to late performance.
People with diabetes are more hypertensive, and diabetic nephropathy often associated with hypertension, hypertension in type 1 diabetic nephropathy in patients with no higher prevalence of hypertension than normal, type 2 diabetes patients with hypertension, but the proportion of hypertension is also elevated when proteinuria occurs. Hypertension is most common in patients with nephrotic syndrome.pre：People with these basic diseases are more likely to suffer kidney disease!