Dietary fiber known as the seventh largest nutrient after the traditional six nutrients, is an essential nutrient for the maintenance of human health and nutrition. However, in recent years, studies have shown that dietary fiber can delay the progress of chronic kidney disease. What is the specific situation?
Dietary fiber is pided into soluble dietary fiber and insoluble dietary fiber. Soluble dietary fiber mainly play a metabolic function, reduce blood cholesterol and postprandial blood glucose, reduce the accumulation of toxins in the body; insoluble dietary fiber can soften the stool, increase the volume of excrement, accelerate intestinal peristalsis, can be used to prevent anorectal disease.
Patients with chronic kidney disease have varying degrees of inflammation, with the decline of renal function, inflammatory response is getting higher and higher. Dietary fiber can inhibit the expression of proinflammatory cytokines and change the inflammatory signal pathways, thereby preventing the occurrence of inflammation. Butyric acid can inhibit the production of inflammatory cytokines.
Chronic kidney disease patients, especially those who have to kidney failure, uremia, most have nausea, vomiting, loss of appetite and other symptoms. This is because of intestinal disorders in patients with renal failure, aerobic over-breeding, and anaerobic bacteria (Bifidobacterium, represented by Lactobacilli) was significantly reduced. This can lead to accumulation of toxins in the body of patients with renal failure, malnutrition and other consequences.
The dietary fiber can improve the role of intestinal flora, adjust the proportion and composition of intestinal flora, promote the growth of beneficial bacteria, inhibit the growth of pathogenic bacteria; but also by increasing the quality and volume of stool, mechanical stimulation of the intestinal wall Caused by the intention to promote bowel movements, so that the excretion of the smooth discharge.
Dietary fiber can speed up peristalsis, shorten the residence time of harmful bacteria in the intestine and reduce the retention time of toxins in the intestine; by changing the urea enterohepatic circulation, reduce serum urea; by stimulating the activity of the micro-flora of urea, is conducive to toxins through the feces discharge.
Dietary fiber can delay the progression of chronic nephropathy by anti-inflammatory, improving intestinal flora and decreasing uremic toxin level. Therefore, patients with kidney disease, especially kidney failure and uremia patients may eat more dietary fiber.pre：How does nephrotic patients take medicine to improve the efficacy of the drug?