What are the complications of membranous nephropathy? Membranous nephropathy is a common cause of adult nephrotic syndrome, clinical manifestations of nephrotic syndrome (large amounts of proteinuria, hypoproteinemia, high edema, hyperlipidemia), or asymptomatic, non-nephropathy range of proteinuria. Inappropriate treatment of membranous nephropathy can lead to a series of complications, including coagulation and renal vein thrombosis, combined with anti-glomerular basement membrane crescentic nephritis is the most serious. The following is a detailed description.
Hypercoagulant and renal vein thrombosis: due to membranous nephropathy in blood clotting factor levels increased, platelet adhesion and cohesion increased, antithrombin Ⅲ and anti-fibrinolytic enzyme activity increased, and produce high coagulation. The incidence of renal vein thrombosis in this disease about 50%, with chronic type more common, no obvious symptoms, but aggravate membranous nephropathy.
Combined with anti-glomerular basement membrane crescentic glomerulonephritis: due to basement membrane damage, membrane antigen exposure or release can lead to anti-basement membrane antibody formation. Anti-neutrophil antibodies, anti-neutrophil antibodies (ANCA) may be detected in serum.
The above content is a serious complication of membranous nephritis, I believe we all have a certain understanding. There are many complications of membranous nephropathy, each of which can not be ignored. So patients must actively treat the disease, to avoid deterioration of the disease, leading to the occurrence of complications. If you have any other questions, please consult our online doctor or leave us a message, we will reply to you as soon as possible.
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