To prevent the progression of kidney function, controlling blood pressure is a critical step. For the control of blood pressure, patients with diabetic nephropathy with microalbuminuria are advised to choose angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists. These two drugs are long-acting antihypertensive drugs. Can maintain blood concentration for a long time, maintain stable blood pressure levels.
In addition, these two drugs also have the function of reducing protein and protecting renal function. Therefore, diabetes patients with proteinuria with these two drugs to reduce blood pressure, can achieve a double-shot effect.
Medication treatment is critical to control blood pressure, but to avoid impaired renal function, blood pressure control must reach a certain range, and the blood pressure standards are different for patients with different conditions:
For patients under the age of 18 with diabetic nephropathy, mainly type 1 diabetes, blood pressure control can be less than 140/90 mmHg; but for elderly diabetic nephropathy patients with proteinuria, most patients with type 2 diabetes, blood pressure requirements Strictly, it should be lower than 130/80mmHg, but the minimum diastolic blood pressure should not be less than 60, which is more beneficial to protect kidney function.
Strict control of blood glucose levels: General requirements Diabetic nephropathy in patients with glycosylated hemoglobin should be controlled as below 7.0%, more protective of renal function. However, some patients may experience the same problem: taking the same drug in the same amount, but in the event of impaired renal function, the blood sugar will be lower than before? It is important to know that hypoglycemia is no less harmful than hyperglycemia.
This is mainly because some hypoglycemic drugs, such as metformin and some sulfonylureas, need to be filtered and excreted by kidney function. After kidney function is damaged, the excretion function is reduced, which will lead to the accumulation of drugs or some magazines in the body. Causes the blood drug concentration to rise, the blood sugar range is lower and lower, even exceed the safe range.
Therefore, during taking hypoglycemic drugs, patients with diabetic nephropathy should not only monitor the change of blood glucose, but also the change of blood drug concentration to avoid unnecessary injury.
Controlling diet is more conducive to protecting kidney function:
Low-sugar diet to minimize the intake of high-sugar foods or high-growth foods; low-salt diet, daily intake of 5g or less per person is safer, which helps to stabilize blood pressure; high-quality low-protein diet to avoid increased proteinuria, the daily protein intake is about 0.8 g/kg. If there are other conditions, it will be adjusted according to the doctor's requirements.
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