For patients with kidney disease, the most important concern and concern is whether the severity of the disease will develop to uremia. For doctors, in addition to the progression of renal function, the complications that the patients have emerged in the course of treatment. It should also attract attention.
The most typical complication in the middle stage of nephropathy is hypertension. As the early renal function loss is low, the blood pressure will not have too much effect. With the development of the disease, the blood pressure begins to rise, and the patients with nephropathy have more identity-hypertension patients.
Kidney disease and hypertension affect each other. Damage to kidney tissue leads to elevated blood pressure, which increases the pressure of the kidney and leads to damage to renal function. In the long run, if the control is not good, it will create a vicious circle. Accelerate the development of renal failure to uremia. Therefore, to prevent the progression of renal function, it is necessary to maintain stable blood pressure before uremia.
At present, the most effective way to treat hypertension is drug therapy, which has quick effect and great effect. However, some patients often have some "prejudice" to antihypertensive drugs, which leads to unsatisfactory results.
According to the effective time after medication, antihypertensive drugs can be pided into short-acting preparations and long-acting preparations. Short-acting antihypertensive drugs, such as nifedipine, captopril, verapamil, diltiazem, and so on, are commonly used. The duration of these antihypertensive drugs is relatively short. In order to maintain stable blood pressure, it takes a short period of time to keep blood pressure stable. Therefore, if you forget the medication, it will cause blood pressure fluctuation, which is unfavorable to the protection of renal function.
Long-term antihypertensive drugs are commonly found in amlodipine, perindopril, losartan, fosinopril, benazepril, and so on. But some patients may not be aware of their use of antihypertensive drugs, random change of medication, resulting in unstable efficacy, poor blood pressure control, leading to aggravated the condition.
It is suitable for the elderly patients with systolic hypertension and obese hypertension, but it is not suitable for nephropathy patients with gout, hyperlipidemia and diabetes. If used for a long time, it will also cause adverse reactions such as hypokalemia, etc. Therefore, even with a large amount of proteinuria, edema, use should also pay attention to dosage, avoid excessive use of electrolyte imbalance, aggravate renal damage.
The most taboo part of taking antihypertensive drugs is intermittent use, which results in high and low blood pressure, which actually causes more damage to kidney disease than a simple increase in blood pressure. Regular medication should be the rule that every kidney friend formulates for himself, strictly according to the doctor's instructions. Adhere to the daily dose on time, in order to more effective blood pressure, protect renal function.
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