What are atypical hemolytic uremic syndrome symptoms?

What are atypical hemolytic uremic syndrome symptoms?

Atypical hemolytic uremic syndrome is a complement disorder disease, complement regulatory protein H factor, and membrane-assisted protein and serum complement intrinsic components (B factor, complement C3) gene mutation can participate in its disease, the disease easily repeated, the prognosis is very poor, 25% of patients died in the acute phase, more than 50% of the development of end-stage renal disease. Let's take a look at what are atypical hemolytic uremic syndrome symptoms.
Long-term activation of the complement will damage the body lack of complement inhibitory factor cells, and then in the entire circulatory system caused by inflammatory response. Vascular endothelial cells inside the endothelial cells are damaged, swelling, neutrophils and other inflammatory cells will be gathered to the damaged parts (vascular endothelial cells), causing small vascular inflammation. Platelet deficiency, which lacks complement inhibitory factor, is also directly activated by complement, leading to multiple thrombosis in the entire vasculature. Thrombosis and inflammatory response block blood flow in the blood vessels of the body, reducing the blood supply to organs and cells, thus forming hypoxia, leading to organ damage and functional failure, including the brain, kidney, heart and gastrointestinal tract.
The above is introduction of the symptoms of atypical hemolytic uremic syndrome, I believe we all have a certain understanding. If you have any other questions, please consult our online doctor or leave us a message, we will reply to you as soon as possible.

What are atypical hemolytic uremic syndrome symptoms

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