In maintenance dialysis patients are often associated with intractable hypertension, hypertension refers to drug therapy for hypertension, easily lead to cardiovascular disease, and cardiovascular and cerebrovascular complications may cause the death of the patient, the causes are the following three points.
1) The volume of blood increased during maintenance dialysis
About half of the patients with uremia appears volume dependent hypertension in maintenance dialysis period is increased blood volume caused by hypertension, dialysis is not complete, not water and sodium intake in the normal range and other factors can lead to retention of sodium and water, leading to increased blood volume is the main reason.
2) the renin angiotensin system activity increased in the patients
Another reason for uremia maintenance dialysis in patients with elevated blood pressure is the renin angiotensin aldosterone system (RASS) system activity increased, increased the system activity can promote the sustained release of aldosterone caused by renal sodium retention; the RASS reference in the regulation of renal glomerular and renal small Guan Pingheng, caused by reduced blood sodium and small blood vessels heavy ion absorption; reduced glomerular filtration pressure; thereby increasing blood volume, leading to high blood pressure.
3)the sympathetic nervous system sensitivity increased
Increased sensitivity of the sympathetic nervous system of patients, the autonomic nervous system function disorder, reflex sensitivity to volume blood vessels and thus also increased, will lead to hypertension or aggravate.
Why is there to maintain on dialysis uremic refractory hypertension, I believe we all understand, if you have other questions, you can consult our online doctor or give us a message, we will reply to you as soon as possible.
pre：The pathogeny of uremic encephalopathy
next：Several common kidney diseases that can cause uremia