Why is uremic patients convulsive?

Why is uremic patients convulsive?

Uremia actually refers to the body can not produce urine through the kidneys, the body of the metabolism of waste and excessive water from the body, caused by poison. Modern medicine that uremia is a loss of renal function, the body's internal biochemical process disorders arising from a series of complex syndrome. Rather than an independent disease called renal failure syndrome or referred to as renal failure, the term PIORRY and HERITER were described in 1840 after renal failure was presented. So why is uremic patients twitch?
Uremia patients with seizures mainly related to hypocalcemia, kidney is associated with calcium metabolism, one of the endocrine organs, in the kidney synthesis of l, 25 dihydroxyalcitonol mainly increase intestinal absorption of calcium, kidney failure when the kidney The loss of parenchymal cells, the reduction of 1,25 dihydroxycholactone alcohol synthesis, intestinal absorption of calcium to reduce the formation of hypocalcemia, neuromuscular excitability increased so convulsions. Serum calcium is often reduced to 1.5 mmol / l (6 mg%) or even down to 1 mmol / l (4 mg%) in patients with advanced renal failure by detecting levels of serum calcium and electrocardiogram, ), ECG Q-T interval extended.
Uremic patients in the acidosis, the total serum calcium in the free calcium increased, so low calcium can not occur convulsions, often infusion of sodium bicarbonate or sodium lactate correction of acidosis occurs when the acute attack, can cause breathing, heartbeat stop Like, so in the acid when the same time to add calcium.
In the late uremia seen when the muscle spasm, muscle contraction and convulsions, calcium often can not be reduced, may not simply the relationship between serum calcium, and uremia when the brain lesions.
The above is why the uremia why there will be a brief introduction of convulsions, I believe we have a certain understanding, if you do not understand anything or other kidney problems, you can consult our online doctor, or give us a message, we will soon Give you a reply, I wish you a speedy recovery!

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