Drug induced nerve injury: is the cause of polymyxin E, streptomycin, kanamycin, barbital, penicillin, Ding Xianben alcohol and other drug poisoning, manifested as physical disorders, seizures, coma, extrapyramidal syndrome, eighth of cerebral nerve damage.
Mental systemic disease: uremia patients often suffer from some mental diseases. Patients often suffer from dizziness, headache, fatigue, loss of understanding and memory loss. With the aggravation of the disease, irritability, muscle tremors and convulsions can develop, and finally develop apathy, lethargy and coma.
Disorders of the cardiovascular system: worsening of uremia can affect the cardiovascular system. The main manifestation is arrhythmia, heart failure and so on. These symptoms can occur in the middle and late stage of uremia.
Uremic neuropathy: common in glomerular filtration rate 12mL/min after the attack, the clinical manifestations include: peripheral nerve disorder, beginning to restless legs syndrome, leg discomfort, lower limbs deep itching or tingling, ants walk, the evening is aggravating, activity or walking can ease. It can be expressed as burn foot syndrome, foot swelling or tightness, tenderness, and then attack acral feel abnormal and burning, slowing of motor conduction velocity;
Dialysis induced neurological disorders: including dialysis dementia and Wernickle encephalopathy. Dialysis dementia early manifestations of language disorder, stuttering, inattention, memory loss, personality changes, the disease can pause depression, delusions, hallucinations, bizarre behavior, dementia, myoclonus, ataxia, apraxia, epilepsy. Wernickle encephalopathy is characterized by bilateral ophthalmoplegia, ataxia, and triad of the body.
Digestive tract diseases: uremia patients suffer from anorexia, nausea, vomiting or diarrhea and some other digestive diseases. This is mainly due to uremia in vivo will appear intestinal bacteria urease resolve urea into ammonia, ammonia to stimulate gastric mucosal inflammation and multiple superficial ulcer etc.. The patient often complicated with gastrointestinal bleeding.
Uremic encephalopathy: also called renal encephalopathy, its clinical manifestations are mainly in the following aspects: encephalasthenia state; severe physical disease symptoms include depression, mania, delirium, hallucinations and delusions; cognition disorders; asterixis, hand and tongue intention tremor; muscle clonic seizures; ataxia; muscle tremor, tetany etc..
Skin disease: itchy skin is a common symptom in patients with uremia, may be toxic products of receptors in the skin irritation caused by. In addition, the patient's skin is dry, desquamation, and tan. Changes in skin color are the cause of increased pigmentation.
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