As a threat to human life in the high risk disease, uremia, has baffled many patients every year. So what's the clinical manifestations of uremia? We will do the detailed introduction to this, for clinical manifestations of uremia, can be pided into the nervous system symptoms, symptoms of digestive system, cardiovascular system, respiratory symptoms, skin symptoms and so on. Below is what we believe is introduced to these symptoms.
The nervous system symptoms
The symptoms of nervous system is the main symptom of uremia. In patients with uremia, early often have dizziness, headache, fatigue, comprehension and memory loss and other symptoms. With the increase of disease can appear agitated, muscle tremor, convulsions; The development to face indifference, lethargy and coma. The occurrence of these symptoms related to the following factors: (1) the accumulation of some toxic substances may cause nerve cell degeneration; (2) electrolyte and acid-base balance disorders; (3) caused by renal hypertensive cerebral vasospasm, hypoxia and capillary permeability increase, causes the degeneration of nerve cells and brain edema.
The digestive system symptoms
The earliest symptoms of uremia patients with digestive system is loss of appetite or indigestion, and many patients may think this is the symptom of stomach trouble. Illness can appear when anorexia, nausea, vomiting or diarrhea. The occurrence of these symptoms may be related to intestinal bacteria of the hydrolysis of urea to ammonia urea enzyme, ammonia stimulation caused gastrointestinal mucosa inflammation and multiple superficial ulcer and so on. Concurrency is common in patients with gastrointestinal bleeding. In addition to nausea, vomiting, also related to the central nervous system dysfunction.
The cardiovascular system symptoms
Uremic patients with renal hypertension, acidosis, hyperkalemia, sodium, water retention, anemia and toxic substances, such as can occur heart failure, arrhythmia and myocardial damage, etc. Due to urea (may) and uric acid stimulation effect, also can produce sterile pericarditis, patients area before the heart pain, physical exams to smell and fibrin often. Serious when in the pericardial cavity with cellulose and bloody exudate.
Acidosis in patients with slow, deep breathing, serious when visible to the particularity of acidosis Kussmaul breathing (library small breath, also called acidosis big breath). Patients with breath smell of urine, this is because of the bacterial decomposition of urea in the saliva to form ammonia. Serious can appear in patients with pulmonary edema, cellulose pleurisy or lung calcified lesions, such as pulmonary edema and heart failure, hypoalbuminemia, the role of the water retention of sodium and other factors. Fibrinous pleuritis is urea stimulation caused by inflammation; The lung is caused by calcium phosphate in the lung tissue deposition.
Itchy skin is a common symptom in patients with uremia, may be products toxicity caused receptor stimulation to the skin; Someone thinks that is associated with secondary hyperparathyroidism, because after removal of the parathyroid gland, can immediately remove the symptoms of pain. In addition, the patients' skin is dry, desquamation and golden brown. Skin color changes, previously thought to be the urine increased pigment, but with absorption spectrophotometer examination, prove skin pigment melanin. The skin exposed parts, slight trauma can cause skin ecchymosis. Because the body sweat contains relatively high concentrations of urea, so in sweat gland openings with urea white crystalline, called uremic frost.
Above is the symptom of uremia. Uremia disease period there are a lot of discomfort status, we will according to different conditions to adopt the most appropriate method to control and the treatment of uremia, hope that through the above introduction can let the patient to further understand their illness, pressure the pressure that comes with less pain!
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