Nephrotic syndrome is a chronic kidney disease caused by various causes. When it manifests as "three highs and one low", namely, massive proteinuria, highly edema, hyperlipidemia and hypoalbuminemia, it is called nephrotic syndrome . Nephrotic syndrome patients often have thin hair, yellow, pale complexion lost moisture and so on.
Children's nephrotic syndrome can affect the long-term growth and development. Patients with severe nephrotic syndrome can present with acute renal failure. The cause of nephrotic syndrome In addition to primary kidney disease, there are some secondary nephropathy can also lead to nephrotic syndrome. These secondary lesions are common: diabetic nephropathy, lupus nephritis, anaphylactoid purpura nephritis, amyloidosis, cancer and so on.
According to the response of hormone therapy nephrotic syndrome can be pided into hormone-sensitive, hormone-dependent and hormone-resistant type three.
Refractory nephrotic syndrome refers to the hormone-resistant type, hormone-dependent or frequent recurrence, in short, hormone therapy is not sensitive or even ineffective nephrotic syndrome called refractory nephrotic syndrome. Pathological types of refractory nephrotic syndrome include: focal segmental glomerulosclerosis, model nephropathy, membranoproliferative nephritis and so on. In addition to the treatment of these diseases hormone, the more to be combined immunosuppressive agents.
Patients with nephrotic syndrome recurrent illness, no response to hormone therapy, to find the reasons for the treatment effect, such as infection, hypercoagulability, hyperlipidemia, renal vein thrombosis. More importantly, patients with nephrotic syndrome should be renal biopsy as soon as possible, a clear pathological type.
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