When nephrotic syndrome occurs, accompanied by nephrotic patients will have a series of complications, edema, hyperlipidemia, anemia, and so on. At the same time, the immune regulatory system in vivo has undergone tremendous changes, which will lead to abnormal expression of proteins in the body, leading to the emergence of hypoproteinemia.
Nephrotic syndrome hypoproteinemia not only directly affects the human body's need for protein, but also has other effects on the body. Human body is a complex body, its various symptoms are related to each other. Due to the excretion of a large amount of proteinuria, insufficient supply of liver synthetic proteins leads to hypoproteinemia. The occurrence of this phenomenon is very serious nephrotic syndrome harm. After the reduction of protein in the blood. It will lead to the decrease of plasma colloid osmotic pressure and the imbalance of colloidal osmotic pressure, and the water in the plasma will overflow and accumulate into the tissue and body cavity, resulting in high edema of human body.
At the same time, when the plasma water overflow, the water capacity in the blood decreases, and the blood volume to participate in the effective circulation is insufficient. Therefore, the decrease of water in the blood will lead to high blood viscosity and easy to form thrombosis. The onset of these symptoms can exacerbate the progression of nephropathy. Nephrotic syndrome is a disease that has a very high incidence in children. It can have a very negative effect on the child's growth. Therefore, when some symptoms of nephrotic syndrome occur, you should go to hospital immediately.
The causes of nephrotic syndrome are as follows:
Infection with bacteria, such as streptococcal nephritis, bacterial endocarditis, shunt nephritis, leprosy, syphilis, tuberculosis, chronic pyelonephritis with reflux nephropathy, etc. Virus infection in hepatitis B, cytomegalovirus, infectious mononucleosis, human immunodeficiency virus; Parasitic infections are found in Plasmodium, toxoplasmosis, worms, schistosomiasis, filariasis.
Drugs or poisonings, allergic organic or inorganic mercury, organic gold and silver, penicillamine, diacetate morphine, propanecid, non-steroidal anti-inflammatory drugs, trimethyldiketone, etc. Bee sting, snake venom; Allergy to pollen, vaccine, antitoxin, tumour, lung, stomach, colon, mammary gland, ovary, thyroid, leukemia, lymphoma, Willm tumor, etc.
Systemic diseases systemic lupus erythematosus, mixed connective tissue disease, dermatomyositis, Shergren syndrome, allergic purpura, amyloidosis, etc. Metabolic disease diabetes, thyroid disease.
Hereditary diseases congenital nephrotic syndrome Alport syndrome Fabry's disease sickle cell anemia fingernail patellar syndrome fat malnutrition familial renal ensemble and other eclampsia. Chronic rejection, malignant renal sclerosis, renal artery stenosis and so on.
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