Infection is the most common complication and the main cause of death. According to the 1984 international pediatric nephrology research organization, direct or indirect infections accounted for 70% of the deaths in children with nephrosis. Infection is often the cause and precursor of repeated and aggravating illness, and can affect the curative effect of hormone.
The causes of infection are: low humoral immunity (immune globulin in the urine loss, diminished synthesis, increased catabolism); often accompanied by cell immunity and complement system insufficiency; protein malnutrition, edema caused by local circulation; commonly used when corticosteroids and immunosuppressive agents.
In bacterial infection, pneumococcal infection was the main pathogen, and the infection caused by bacteria increased in recent years. There is a common respiratory infection, urinary tract infection, skin erysipelas and primary peritonitis. Generally do not advocate preventive use of antibiotics, because the effect is not reliable, but also easy to cause drug-resistant bacteria proliferation and flora imbalance; but once infection occurs, should be timely and active treatment.
Children are more sensitive to virus infection, especially in the process of glucocorticoid and immunosuppressants accepted, with chicken pox, measles, herpes zoster disease often than the general children; to contact history, hormone and immunosuppressant can temporarily reduce, and give the gamma globulin injection.
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