Nephrotic syndrome is a group of clinical manifestations of glomerular disease, not an independent disease, a large number of proteinuria is a characteristic of nephrotic syndrome, which caused by glomerular capillary filtration membrane damage. It may be primary nephrotic syndrome, may also be secondary nephrotic syndrome. Most adults and children with nephrotic syndrome as primary, in our country secondary nephrotic syndrome is the most common cause of systemic lupus erythematosus, Henoch Schonlein purpura, and diabetes.
Pediatric nephrotic syndrome is characterized by "three high and one low" that is highly swollen, high proteinuria, hypercholesterolemia and hypoproteinemia. Symptoms of nephrotic syndrome are often an important aspect of pre-onset nephrotic syndrome patients.The symptoms of nephrotic syndrome are more obvious than those of other nephrotic symptoms and are easily detected by the patient. In addition to routine examination found that kidney disease, nephrotic syndrome and which should pay attention to it, experts say to understand the symptoms of nephrotic syndrome, careful observation of their own physical changes is an important aspect of the discovery of nephrotic syndrome.
Whole body edema is the most significant symptoms of nephrotic syndrome. The occurrence and severity of edema were positively correlated with the degree of hypoproteinemia. Known as renal edema, due to a large number of proteinuria caused by low plasma protein. Another reason is the decline in glomerular filtration, and renal tubular reabsorption of water and sodium is still good, resulting in water and sodium retention flow, tissue gap in the retention of water, light eyelid and facial edema, severe systemic edema or there is pleural effusion, ascites. Mainly seen in nephritis edema. Almost all patients with nephrotic syndrome will be varying degrees of edema, edema can be sustained for several weeks or months, or in the whole course of time swollen. Infection, often so that swelling or relapse, or even azotemia. At this time often show anorexia, nausea, vomiting, abdominal distension and other symptoms of gastrointestinal disorders.
Severe edema such as nephrotic syndrome patients with lower limbs or systemic edema, persistent refractory, will seriously affect the work and life. Get rid of nephrotic syndrome, can not blindly go with the lifting of edema. The key is to repair the damaged glomerular innate cells, which can radically eliminate edema.
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