Does the infection aggravate nephrotic syndrome in children?

Does the infection aggravate nephrotic syndrome in children?

Pediatric nephrotic syndrome patients must be to prevent infection, the impact of infection on patients is fatal, because infection is caused by children with nephrotic syndrome, the most common complications of death, is also the cause of death in children with nephrotic syndrome, the main reason.

According to the 1984 International Children's Nephropathy Research Organization (ISKDC) statistics, directly or indirectly due to infection in children with nephrotic syndrome patients accounted for 70% of children with kidney disease death. Infection is often repeated nephrotic syndrome and aggravated incentives and lead, and can affect the efficacy of hormones.

Nephrotic syndrome prone to infection are due to: humoral immune function is low (immunoglobulin from the urine loss, synthesis decreased, increased metabolic metabolism); often accompanied by cellular immune function and complement system dysfunction; protein malnutrition, edema caused by local Circulatory disorders; commonly used when the application of corticosteroids, immunosuppressive agents. Bacterial infection in the past mainly to pneumococcal infection, infection caused by recent bacilli also see increased (such as E. coli). Common respiratory infections, urinary tract infections, skin erysipelas and primary peritonitis. Generally do not advocate the prevention of antibiotics, because the effect is unreliable, and easily lead to drug-resistant strains of proliferation and flora; but in the event of infection should be timely and active treatment. 

Nephrotic syndrome in children infected with the virus is also more sensitive, especially in the process of receiving corticosteroids and immunosuppressive agents, complicated by chickenpox, measles, herpes zoster when the kidney is often more severe than the average children; Respiratory history of children with nephrotic syndrome, hormones and immunosuppressive agents can be temporarily reduced, and given-gamma globulin injection.

Through the introduction of the above, we know that infection in children with nephrotic syndrome is a great impact, and even life-threatening, children with nephrotic syndrome patients must avoid infection. If you have any other questions, please consult our online doctor or give us a message, we will reply to you as soon as possible.

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