Why lupus kidney disease cause hair loss?

Why lupus kidney disease cause hair loss?

Why lupus kidney disease cause hair loss? 

Lupus erythematosus (sle) is an autoimmune disease, can drag the body systems and organs, in the patient's blood and organs can find a variety of autoantibodies. Lupus erythematosus (sle) patients with genetic factors, in some internal and external factors, such as virus infection, sunlight, trauma, drugs, triggering the immune system diseases, such as pregnancy, the production of various kinds of resistance to their organization, antibodies and immune complex, causes the body's own tissue, such as skin, blood vessels, heart, liver, kidney, brain and other organs and tissues, inappropriate treatment easily broke out many times, each time recurrence might worsen. Lead to the patient may cause hair loss. Why lupus kidney disease cause hair loss? 

1, the disease is more and more young and middle-aged women. 

2, good hair and exposed part, such as the face, neck, and upper body, arms outstretched, his brother, is to point to (foot), can influence the oral mucosa. 

3, her lesions mainly has two types: 

(1), annular erythema type: expression is round or curved, edema, erythema, edge uplift; 

(2), papules scales: display size from invasive erythema, papula, sparse coverage scales; 

4, photosensitive, hair loss, Renault phenomenon, such as fever, arthralgia, serositis, kidney damage, and the central nervous system damage and less light, anemia, leukopenia, thrombocytopenia, a positive ana, immunoglobulin, Ro/SSA, La/SSB antibody positive. Second, lupus erythematosus (sle) patients may lead to hair loss is that true? 

Lupus erythematosus (sle) patients may lead to hair loss, in addition to the loss of hair inflammation caused by skin rash and other places also hair loss, is not only the hair and eyelashes. Eyebrows, hair will fall down. 

Hair comes in two forms: one for the diffuse hair loss, lose luster, or yellow, the rest of the hair, hair dry, easily broken, forming loose hair or bald; Another kind of hair loss on the forehead, often say "bang", thinning hair, withered and yellow, fragile, hair length is uneven, form a "hair" lupus erythematosus (sle). 

Lupus erythematosus (sle) hair loss caused by the peace "seborrheic hair loss" is completely different, different pathological basis. Under the skin with lupus hair loss is mainly due to the small vasculitis, lead to hair follicles nutrition supply, make the hair growth. This is lupus erythematosus (sle) part of the clinical manifestations, pathogenesis of disease in patients with lupus erythematosus (sle) began to hair loss, so to attract attention, lupus erythematosus (sle) is common hair loss. 

After general control, the hair can regenerate. In particular, lupus erythematosus (sle) patients again hair loss is probably the first recurrence of symptoms, attract the attention of doctors and patients. 

Joint pain, joint pain, more than 90% of the patients disease may occur. Joint pain, there a few years ago has emerged, some joint surrounding soft tissue swelling, tenderness and fluid, acute arthritis. The affected areas to see more proximal joints, joints, wrist, elbow, knee, foot part, and so on, often symmetry. Morning stiffness for some patients. Some patients joint duration is longer, and the patient seems to be only a very short period of time, or joint pain. 

X ray is mainly see the concerns of the bone changes and deformity, long-term use of glucocorticoid for more than five years, about 5% of the patients can have aseptic osteonecrosis. 

Reduce blood cells: because autoantibodies, red blood cells, white cells and platelets own ruin. Anemia is mainly cell anemia, red blood cell antibody lgG greater resistance, hemoglobin and decline. White blood cells usually granulocyte and lymphocyte. Thrombocytopenia, survival time is very short, because of its surface lgG platelet platelet destruction caused by itself. 

Heart damage, pericarditis, about a quarter of the patients with mild symptoms may be absent, clear the area before the heart pain, chest tightness, pericardial friction moment of voice, clinical couldn't find it. Cardiac ultrasound or B ultrasonic and X-ray chest radiograph need regular check, can display the pericardial effusion. In the hospital treatment of patients with systemic lupus erythematosus (sle) pericardial effusion (34.15%) were found. 

Lung injury: many patients with systemic lupus erythematosus (sle) in the two lung X-ray chest radiograph, and articles of basal segment nodules or reticular shadows, interstitial change, most have no symptoms. 

Pleurisy can be asymptomatic, is only found in the following inspection, namely. B ultrasonic and X-ray sternum small to moderate amount of pleural effusion, sometimes with pericardial effusion. Pleural effusion LE cells can be found. 

And lupus nephritis: from about 75% of the patients with systemic lupus erythematosus (sle) have clinical renal damage, urine protein, red blood cells, white blood cells, a few patients with tube type. In the early days of lupus nephritis. Pathological changes for several years, may have a wide range of damage and renal insufficiency, the evolution of uremia. 

Brain damage nerve injury: systemic lupus erythematosus (sle) have all kinds of performance. Mental illness is characterized by schizophrenia reaction, a variety of mental disorders, such as irritability, insomnia, illusion, suspicion, delusion, strength, and so on. 

Brain injury is a common systemic lupus erythematosus (sle) end-stage chronic or acute severe cases, systemic lupus erythematosus (sle) have some slow raw mild brain injury cases, often have a headache giddy, electroencephalogram (eeg) had abnormal changes, at the start of the emergency period hair very rare cases symptoms. In general, after timely treatment, brain damage is reversible, abnormal electroencephalogram (eeg) and brain CT scans of the change is reversible. 

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