The etiology of most chronic nephritis patients is unclear. The clinical characteristics are long course of disease, and there may be asymptomatic period of time, which shows a slow progression. Here, experts explain the difference between acute glomerulonephritis and chronic glomerulonephritis.
Urine routine examination has varying degrees of proteinuria, sediment microscopy can be seen red blood cells, the majority of patients have varying degrees of hypertension and renal dysfunction. Chronic nephritis clinical manifestations are similar, but the pathological type and severity of lesions vary. According to the majority of glomerular major lesions, pided into mesangial proliferative glomerulonephritis, membranous nephropathy, focal segmental glomerulosclerosis, mesangial capillary glomerulonephritis, hyperplastic sclerosing glomerulonephritis.
Acute streptococcal infection after nephritis delayed healing, the course of more than 1 year can be transferred to chronic nephritis. However, most of the chronic nephritis is not extended by acute nephritis, generally due to long-term immune mechanism and long-term changes in renal hemodynamics, renal vascular changes, mesangial function caused by changes.
Previously considered that acute glomerulonephritis if proteinuria and microscopic hematuria for 6 months to 1 year or more that has been transferred to chronic, renal biopsy and clinical data in recent years found that acute renal inflammation after renal abnormalities and renal biopsy activity in 2 to 3 years gradually disappear. So we should not judge the difference between acute and chronic glomerulonephritis only by time. According to follow-up data found that the clinical manifestations of acute glomerulonephritis disappeared in the kidney can still have residual lesions, but sometimes glomerular fibrosis, and sometimes patients with urinary routine examination is still found in protein and red blood cells, and biopsy found that the kidney in the diffuse inflammatory lesions have disappeared, only the residual lesions, the so-called "defective healing." Some patients with the follow-up time, biopsy found in the glomerular fibrosis increased trend. In case of the above situation should continue to follow-up observation, pay attention to the possibility of development of chronic glomerulonephritis.
Chronic nephritis patients have acute onset of disease in each tendency, the situation is relatively stable, due to respiratory tract infection or other malignant stimulation, in the short term (3 ~ 5 days or even 1 ~ 2 days) disease acute exacerbations, when patients with massive proteinuria, hematuria, and even increase the tube type. Marked edema and hypertension, as well as deterioration of renal function. After proper treatment, the condition can be relieved and basically restored to its original level. It may also lead to disease progression and into uremia.
The above is our experts for everyone to explain the difference between acute glomerulonephritis and chronic glomerulonephritis , if you have knowledge about kidney disease need a detailed understanding, you can consult our online experts.
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