What are the factors that affect glomerular filtration rate? Glomerular filtration membrane permeability and total filtration area; effective filtration pressure; renal blood flow. The abnormalities of these three factors are possible to affect glomerular filtration rate, thus affecting the formation of urine, leading to oliguria. The following is a detailed introduction, we hope to help.
Factors affecting the glomerular filtration rate: glomerular filtration membrane permeability and the total filtration area.
Glomerular filtration membrane lesions can cause increased permeability, it will lead to increased urine output, varying degrees of proteinuria, hematuria; and if the glomerular filtration membrane permeability decreased, it can lead to oliguria.
Glomerular filtration membrane filtration area will also affect the glomerular filtration rate. The total area of the glomerular capillaries on both sides of the human body is more than 1.5㎡, late glomerular lesions, glomerular fibrosis or vitreous changes can obviously reduce the filtration area and lead to oliguria.
Factors affecting glomerular filtration rate: effective filtration pressure.
There are three factors that make up the effective filtration pressure: glomerular capillary blood pressure, plasma colloid osmotic pressure, renal capsule pressure. Changes of any one of these factors affect the change of glomerular filtration rate.
Factors affecting glomerular filtration rate: renal blood flow
The ratio of glomerular filtration rate to renal plasma flow is called the filtration fraction. Glomerular filtration rate and filtration fraction are indicators of renal function. If the glomerular filtration rate is too high can cause hematuria and proteinuria, severe cases can lead to nephritis and so on.
What are the factors that affect glomerular filtration rate? The above is a detailed introduction, the factors affecting glomerular filtration rate are glomerular filtration membrane permeability and total filtration area, effective filtration pressure and effective filtration pressure, no matter which of them has problem, it will have an impact on the glomerular filtration rate, so patients must pay attention to it, and immediately seek for medical attention once there is discomfort.
Beijing In China