What is the symptom of hereditary nephritis?

What is the symptom of hereditary nephritis?

Hereditary nephritis (Alport syndrome, AS) is a hereditary glomerular basement membrane disease characterized mainly by hematuria, progressive loss of renal function, sensorineural hearing loss, and ocular abnormalities. The following is a detailed introduction to symptoms of hereditary nephritis.
Nephritic syndrome and chronic renal failure: hematuria is the most common manifestations of this disease, almost 100% of the patients had hematuria, but most are found under the microscope to microscopic hematuria, so the onset may be hidden. Hematuria can be aggravated after strenuous exercise or upper respiratory tract infection, or even pink or tan gross hematuria.
Deafness: 40%-60% patients with deafness, often nerve, and more need electric audiometry can be found. There was no significant correlation between the severity of deafness and the pathological changes of kidney.
Eye abnormalities: mainly conical or spherical crystals, deposits of white granules around the macula. There are other nonspecific abnormalities, such as vision abnormalities, cataracts, etc..
Other manifestations: the disease is often combined with other abnormalities, such as multiple peripheral neuropathy, muscle atrophy, thrombocytopenia, multiple malformations, seizures, abnormal EEG, etc..
What is the symptom of hereditary nephritis? The above content is described in detail, we hope to help you. If you have any further questions, please contact our online doctor or leave a message for us. We will reply to you as soon as possible.

 What is the symptom of hereditary nephritis

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