There are many reasons for the reduction of urine in patients with glomerulonephritis, mainly in the following aspects:
1, the early stage of acute glomerulonephritis, due to the body's immune response and inflammatory response, so that the small arteries of the whole body, including renal vascular spasm, and significant ischemia, capillary effective filtration pressure reduction, urine generation decreased.
2, the immune response caused by the glomerular basement membrane non-specific inflammatory lesions, so that the basement membrane thickening, swelling or rupture, resulting in reduced glomerular filtration area, filtration rate decreased, reduced urine production.
3, glomerular capillary endothelial cells, glomerular epithelial cells and capillary interstitial cell hyperplasia and swelling, may be a compensatory response against basement membrane injury, but the cell hyperplasia and swelling at the same time, and the infiltration and fibrin deposition of polymorphonuclear leukocytes, resulting in a narrow lumen even so, blocking blood flow blocked, glomerular filtration reducing ischemia.
The above is about why does the patient with acute nephritis have oliguria, when the body appears abnormal, must check in time, timely diagnosis of disease, good prevention and treatment.
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