Urine examination: gross hematuria or microscopic hematuria, with severe red cell urine under phase contrast microscope. White cell, epithelial, red cell, tubular, granular, and occasionally white cell types were also seen. Proteinuria is usually 0. From 5 to 3.5g/d, a small number of patients can develop nephrotic syndrome with proteinuria. Recovery of urinary changes, most children and adults around 1/2 turn negative in 4~6 months, a few can be delayed for one year, microscopic hematuria can be delayed for one to two years.
Immunological examination: elevated ASO titer is evidence of recent streptococcal infection. More than 3 weeks after streptococcal infection, titers increase and begin to decrease in 3~5 weeks, and 1/2 patients return to normal within six months. But in acute nephritis, ASO negative can not deny the history of Streptococcus pneumoniae infection. CIC can be positive in acute stage.
Most patients with CH50 and C3 decreased significantly and recovered more than 6~8 weeks. If continued, other diseases such as mesangial capillary nephritis and systemic lupus erythematosus should be considered. In addition, blood fibrinogen increased and urinary FDP (fibrin degradation products) increased, which correlated with coagulation and fibrinolysis of the kidneys during acute nephritis, and the results were consistent with the severity of the disease.
Blood test: blood routine showed slight anemia, related to water and sodium retention and hemodilution. If the foci are present, there may be an increase in white blood cells. ESR can be increased, oliguria can occur in patients with hyperkalemia, blood volume expansion obviously dilutional hyponatremia, may have mild hyperchloremic acidosis, hemodilution causes mild hypoproteinemia and hypoalbuminemia were nephrotic syndrome seen in a serious and elevated blood lipids.
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