Long term use of drugs has great pressure on the kidneys, but many people have to rely on drugs for the treatment of diseases. Here are some of the symptoms of nephritis that have been prescribed for long periods of time.
Kidney damage is a clinical problem currently by many patient’s concern, and the deceased kidney disease patients with acute deterioration of renal function due to the application of nephrotoxic drugs. The renal blood supply is great, is intended as a filter and waste metabolism, their blood volume accounted for 1/4 of the whole, are bigger than any organ, a good kidney function, on the other hand, a large number of drugs through the kidneys. The drug arrived by the kidneys, there are many drugs required by the kidneys and excreted, and the renal tubular reabsorption and excretion has effect on some drugs, like in the renal tubules of the drug concentration is high, kidney damage greatly increases the chance, and in the kidney glomerular filtration area. Drug contact with the corresponding area is large.
Drug damage to the kidneys in two ways, one is direct damage, such as renal toxicity drugs can be directly associated with renal tubular injury, drug concentration, crystallization and sulfa drugs can cause kidney obstruction and mechanical damage. The other is a lot of damage, indirect damage, its main allergic reaction; damage, injury, immune complexes and hemodynamic changes of Hemorheology damage, electrolyte disorder caused by damage, drug damage to the kidneys can directly lead to renal tubular necrosis; osmotic nephropathy; glomerular nephritis or other changes; obstructive nephropathy.
At the same time, for those with impaired renal function, such as the elderly and chronic kidney disease patient, it is more common to lead to a further decline in renal function. It should be noted that some drugs are commonly used drugs for kidney patients, such as diuretics, it should be take under the guidance of a doctor, can not purchase and take medicine by yourself, kidney patients need under the guidance of doctor medication.
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