Blood routine examination: lower urinary tract infection, white blood cells are generally normal or mild increase. Upper urinary tract infection, the white blood cells were significantly increased, and neutrophil nucleus left shift phenomenon; chronic leukocytes change little or slightly elevated, but often different severity of anemia, erythrocyte sedimentation rate can be accelerated.
Kidney function examination: the kidneys is to maintain the body environment which is an important organ, its function is to discharge metabolic waste, maintain water, electrolytes, acid and alkali and osmotic pressure balance, retain useful substances and endocrine function. The purpose of renal function tests is to understand whether the kidney is damaged and the degree of damage and damage to the site. In acute pyelonephritis, the general function of renal shows no more changes, occasional mild renal dysfunction, but after treatment can be restored. Pyelonitis is the main lesion of renal medulla interstitial inflammation, therefore, renal tubular and collecting tube first involved, so early can have renal tubular dysfunction. Concentration function is one of the earliest signs of pyelonephritis, pyelonephritis and cystitis can be used as a differential diagnosis. But because of pyelonephritis renal concentration dysfunction is only about 1/3, so this test is not a sensitive test.
Chronic pyelonephritis renal tubular dysfunction often more than glomerular. In the early stages of this disease, glomerular function can be completely normal, but there have been renal enrichment dysfunction. Due to renal tubular dysfunction, the patient may be renal diabetes and sodium and potassium loss, and uric acidosis due to high blood chloride acidosis. Late in addition to renal tubules, glomerular function is also an obstacle, decreased glomerular filtration rate, decreased renal blood flow, serum creatinine, elevated urea nitrogen, creatinine clearance decreased, eventually leading to renal failure.
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