Many patients with lupus nephropathy, do not know why in the treatment of this disease, but also blood test indicators. For this problem, the following experts to explain to you.
Before understanding the blood test indicators of lupus nephropathy, first of all we first come to understand what is the cause of lupus nephropathy? General lupus kidney pathogenesis - immune disorders, including lupus kidney disease itself, the body's immune tolerance abnormalities, B cell hyperactivity , T cell dysfunction and cytokine abnormalities. Lupus nephropathy - Immune complex deposition. Lupus kidney disease process, will produce a variety of self-organization, including the nucleus, cell membrane, cytoplasm and various tissue components of the autoantibody. Among them, anti-nuclear antibody (ANA) is the most important, it is systemic lupus erythematosus onset, diagnosis and disease have played a key role. Systemic lupus erythematosus complicated with kidney disease, the patient will have antigen-antibody immune complex and the original immune complex deposition in the glomerular, causing kidney damage, that is, lupus nephropathy.
Often, hematological parameters are usually checked regularly during the treatment of lupus nephropathy. The purpose of blood test indicators is to early detection of disease activity, early adjustment of treatment. Do not wait until the symptoms were only referral, because at this time organ damage is already very serious. It is generally thought that leukocytes or thrombocytopenia or anemia are clearly symptoms of lupus nephritis. Anti-dsDNA positive in blood. ANA level increased. Complement down. Erythrocyte sedimentation rate ("50 mm / hour or more). C-reactive protein and cold globulin increased reflect lupus activity. Lupus activity is generally abnormal hematological indicators, and then only symptoms.
There is also Beijing Tong Shantang Chinese medicine hospital kidney disease experts pointed out that the incidence of lupus nephropathy can be asymptomatic proteinuria / hematuria, acute nephritis syndrome, chronic nephritic syndrome, acute nephritis, nephrotic syndrome, chronic renal function Incomplete and other performance. Immunological changes include anti-DNA antibodies and a variety of autoantibody levels, serum complement decreased, circulating immune complex increased. Timely treatment is the key to improving the prognosis of patients with lupus nephritis. Conventional drugs for the treatment of lupus nephritis are hormones, depending on the degree of clinical manifestations and histological changes. Clinical practice has shown that the combination of cytotoxic drugs is more effective than hormone therapy alone.
Through the above description, I believe we have a blood test of lupus nephropathy, with a certain understanding, if you have other problems, you can consult our online doctor or give us a message, we will reply to you as soon as possible.
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