Chronic glomerulonephritis referred to as chronic nephritis, refers to proteinuria, hematuria, high blood pressure, edema as the basic clinical manifestations, different ways of disease, disease progression, slow progress of the disease, may have varying degrees of renal dysfunction, Functional deterioration tendencies and eventually develop a group of glomerulopathy with chronic renal failure. As the disease type and disease of this group is different, the main clinical manifestations may vary. Disease performance was persified.
Where urine test abnormalities (proteinuria, hematuria, tubular urine), edema and hypertensive disease for more than a year, with or without renal damage should be considered the disease, except in patients with secondary glomerulonephritis and hereditary kidney After pelvic nephritis, clinically can be diagnosed with chronic nephritis.
Differential diagnosis: secondary glomerular diseases: such as lupus nephritis, allergic purpura nephritis, diabetic nephropathy, according to the corresponding system performance and specific laboratory tests, generally difficult to identify.
AIport syndrome: often onset in adolescents, patients with eye (ball lens, etc.), ear (nerve deafness), kidney (hematuria, mild to moderate proteinuria and progressive renal dysfunction) abnormalities, and positive family History (mostly sexually explicit inheritance).
Other primary glomerulopathy: symptomatic hematuria and / or proteinuria (occult glomerulonephritis: urinary protein <1g / d, no edema, hypertension and renal dysfunction. Acute nephritis, some chronic nephritis When the disease is more acute, much like acute nephritis, but most of the characteristics of acute nephritis did not show: precursor infection from nephritis 1 to 3 weeks, a transient complement C3 decline, self-healing tendency to help identify.
Essential Hypertensive Renal Damage: Chronic nephritis with markedly elevated blood pressure is required to identify secondary hypertension with primary secondary hypertension (ie, benign small arterial nephrosclerosis), followed by longer-term hypertension, followed by Renal damage, mild changes in urine (trace to mild proteinuria, may have microscopic hematuria and tube type), often other high blood pressure target organ (heart, brain) complications.
Chronic pyelonephritis: more recurrent episodes of urinary tract infection, and imaging and renal dysfunction, urinary sediment often white blood cells, urine bacteria can be positive distinction.
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