Diabetic nephropathy (DN) is defined as diabetic glomerulopathy associated with abnormal glucose metabolism. It is a part of systemic microvascular disease and a major manifestation of diabetic kidney damage. At present, approximately 4000 diabetic patients die from the disease in the United States each year. In some dialysis centers, the number of hemodialysis patients or hemodialysis patients with DN is 1/4 of the total number of dialysis patients. Studies have shown that the incidence of diabetic nephropathy is different from type of diabetes, age of onset and course of disease.
Diabetic patients who are ill before the age of 20 have about 50% chance of developing diabetic nephropathy after 20 years of age. On the contrary, ill after the age of 40, to get sick after 20 years only 2-4% chance of occurrence of diabetic nephropathy, according to the Baer report, also at the age of 20-40 patients, history within 10 years the incidence of DN was 3%, 10-20 was 50%, and in the history of more than 20 years of nearly 100% nephrotic microangiopathy.
Statistics indicate that insulin dependent clinical type DN diabetes incidence rate is about 40%, about half of the patients with type 2 diabetes caused by DN died of uremia. Become the main cause of death among young patients. The incidence of clinical non insulin dependent type DN diabetes and uremia caused by DN was significantly lower than that of patients with type 1 diabetes, but research shows that the development of patients with type two diabetes can aggravate cardiovascular and retinal complications. According to a study published in 1998 by WTO, patients with type two diabetes had a higher risk of cardiovascular complications than those with negative proteinuria. As mentioned above, DN is an important complication of diabetes mellitus, especially of type 1 diabetes, which seriously affects the life and health of diabetics.
Diabetic nephropathy belongs to the category of diabetes, lumbago, Guan Yu and so on. Chinese medicine has a better understanding of this disease. It has a detailed record from the etiology, pathogenesis and clinical treatment, and has accumulated a wealth of clinical experience. In recent years, TCM has made further research on this disease and made rapid progress. Especially with the advanced technology and theory of modern medicine, the curative effect of this disease has been further improved.
On the basis of summing up the experience of our predecessors, and through long-term clinical observation, we believe that the pathogenesis of this disease is mainly diabetes, lingering lingering, making the viscera dysfunction, yin and Yang, Qi and blood weakness and incidence. The Zang Fu organs of the viscera focus on the three viscera of the liver, spleen and kidney, while the other three involve phlegm, blood stasis and water. The clinical use of Spleen Qi, tonifying the liver and kidney, blood and water treatment preparation combined with syndrome differentiation, with elements of Tangshenkang series of traditional Chinese medicine in treatment of diabetic nephropathy has achieved satisfactory clinical effect, the general three months can not only eliminate the symptoms, reverse disease, recovery of renal function and eliminate proteinuria, at the same time the whole reversed diabetes.
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Beijing In China