Heart failure is a serious complication and an important cause of death in CRF, heart failure of CRF is the result of a variety of factors, including:
Excessive blood volume: At CRF, the volume of blood increases, the left ventricular end diastolic volume, cardiac output and cardiac output increase, and the left ventricular function declines and leads to heart failure when the care function is not compensated.
Hypertension: long-term high blood pressure so that the heart load is too heavy, causing ventricular wall hypertrophy, heart expansion, a long time caused by heart failure. The concentration of plasma catecholamine increased in uremia, and its elevation was closely related to the occurrence of heart failure. In addition, hypertension accelerates the progression of atherosclerosis and leads to heart failure.
The role of uremic toxins: In CRF, harmful metabolites accumulate in the body, which inhibit myocardial disease, lead to myocardial dysfunction and heart failure.
Disturbance of electrolyte metabolism and acidosis: In CRF, electrolyte disturbance leads to changes in myocardial electrical and myocardial excitability, leading to cardiac arrhythmias and heart failure.
Renal anemia: long-term anemia in patients with CRF, myocardial hypoxia, myocardial dysfunction. As the body's compensatory heart rate increases, cardiac output increases, and over time, the heart due to overload, myocardial hypoxia can lead to heart failure.
Dialysis arteriovenous fistula: Because of the large volume of blood flow and the increase of cardiac load, it can lead to heart failure for a long time.
Atherosclerosis: CRF complicated with hypertension and hyperlipidemia after dialysis can accelerate the progression of atherosclerosis, increase the mortality of CRF, and often die from myocardial infarction during dialysis.
Immunity is low: when uremia,easy to cause infection because of low immunity, and cause infection after myocarditis or pericarditis, leading to heart failure.
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