In normal life, chronic kidney disease has been difficult to treat, not only complex and long course of disease, chronic renal failure is one of the typical example. When the disease is associated with urinary tract infection, the patient's suffering is extremely serious. Then, how should we treat the chronic kidney failure patients with the characteristics of this disease?
First of all, we need to understand that when the infection, the cure of chronic renal failure is extremely difficult, the main reason is the renal atrophy in chronic renal failure, blood flow is poor, the drug is not easy to reach the effective concentration to obtain effective antibiotic concentration not to cause poisoning difficult in blood and urine; effective concentration of antibacterial drugs in in kidney do this very slowly to reach, so prone to bacteria resistance; infection is usually in the hospital income, pathogens for drug resistant strains; bilateral renal damage is not equal, antibacterial drugs in different concentration on both sides of the kidney, the concentration of antibacterial drugs on the side of poor renal function is low, can not play a role.
It can be seen that the incidence of chronic renal failure is difficult to cure, but patients should not lose confidence. Because the kidney is the main route of excretion of many antibiotics, chronic renal failure when the drug excretion delay, easy to accumulate, increase renal toxicity, therefore, chronic renal failure combined with urinary tract infection safe and effective use of antibiotics, should be based on drug sensitivity, antibiotics The major metabolic processes, the excretion pathway, the toxicity to the kidneys, the creatinine clearance rate in combination with the patient, and whether the patient is dialysis treatment to determine the type of antibiotic, the route of administration, the method of administration and the dose.
Beijing In China