There are many types of failure disorders. Can be pided into acute renal failure and chronic renal failure, both of them will endanger our health, if not timely treatment, will cause decreased renal function.
Renal function compensation period: the renal function compensation period, glomerular filtration rate for normal glomerular filtration reduced a lot. Renal units also decreased. Renal reserve capacity has been lost, but for the excretion of metabolites, regulation of water electrolyte and acid-base balance ability is good, so no special clinical manifestations, serum muscle enzymes and blood urea nitrogen is usually normal or sometimes slightly increased.
The period of hypoxemia: the glomerular filtration rate is less than the normal glomerular filtration rate in the diabetic stage, but the nephron decreases considerably. Renal concentrating dysfunction, nocturia or polyuria, varying degrees of anemia, often with nitrogen, serum creatinine, urea nitrogen increased. Clinical can have fatigue, anorexia, nausea and mild discomfort all over the body. This period of time, such as neglect of renal function or extra body burden, can present severe symptoms. If the infection or use of nephrotoxic drugs, can cause rapid decline of renal function and failure.
Renal failure stage: in this period, may not keep the stability of the internal environment, so that the serum creatinine and urea nitrogen were significantly increased, urine concentration and dilution dysfunction, acidosis, retention of water and sodium, low calcium, high phosphorus and high potassium balance disorders such as performance. There are obvious anemia and gastrointestinal symptoms. Also can have nerve, mental symptom to wait for a symptom to appear.
Uremia period: this stage is the late stage of chronic renal failure, the clinical symptoms of these renal failure are more obvious, manifested as systemic multiple organ failure, metabolic system is seriously unbalanced. The clinical manifestations of nausea and vomiting, irritability, increased blood pressure, palpitation, chest tightness, not supine, dyspnea, severe anemia, severe convulsions, coma, often with hyperkalemia, hyponatremia, hypocalcemia and hyperphosphatemia. This phase relies on dialysis to support life.
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