Symptoms of chronic renal failure in different stages

Symptoms of chronic renal failure in different stages

Various kidney diseases are becoming more and more common in the society. Healthy people are trying to prevent the occurrence of chronic renal failure. The people who are ill are struggling with the disease. Well, if we suffer from chronic renal failure, what are the common symptoms in the clinic? Here are the symptoms of chronic renal failure in different stages.
The first stage, renal function compensation period: the normal glomerular filtration rate is 120 ml per minute. Glomerular filtration rate is reduced to 30-60 ml / minute, and nephron reduction is approximately 20%-25%. The renal reserve capacity has been lost, but for the excretion of metabolites, regulation of water electrolyte and acid-base balance ability is good, so no special clinical manifestations, serum muscle enzymes and blood urea nitrogen is usually normal or sometimes slightly increased.
Second, azotemia period: this period of glomerular filtration rate decreased to 25 ml / min, nephron reduction 50%-70%, concentration of renal dysfunction, appeared nocturia or polyuria, often have varying degrees of anemia, azotemia, serum creatinine, blood urea nitrogen levels. Clinical can have fatigue, anorexia, nausea and mild discomfort all over the body.
The third stage, renal failure stage (early stage of uremia): renal function is seriously damaged, it can not maintain metabolism and water, electrolyte and acid-base balance in the body. The results showed that serum creatinine and urea nitrogen increased significantly, urinary concentration, dilution, dysfunction, acidosis, water and sodium retention, low calcium, high phosphorus, high potassium and other imbalance performance. Can have obvious anemia and gastrointestinal symptoms, such as nausea, vomiting, loss of appetite. Also can have the neuropsychiatric symptoms, such as fatigue, inattention, depression etc..
The fourth stage, uremia period: manifested as multiple organ failure, such as gastrointestinal, nervous, cardiovascular, hematopoietic, respiratory, skin and metabolic systems seriously unbalanced. The clinical manifestations of nausea and vomiting, irritability, increased blood pressure, palpitation, chest tightness, not supine, dyspnea, severe anemia, severe convulsions, coma, often with hyperkalemia, hyponatremia, hypocalcemia and hyperphosphatemia. This phase relies on dialysis to support life. Often due to hyperkalemia, cerebral edema, pulmonary edema, heart failure and sudden death.
The above is an introduction to the symptoms of chronic renal failure in different stages. From the onset of chronic renal failure to the end, if the period is not intervened, the patient will experience four different periods in turn, with each patient exhibiting a different symptom during each of these periods. The final more difficult to cure, so for chronic renal failure to do early detection and early treatment. If you have other questions, you can consult our online doctor or give us a message, we will reply to you as soon as possible.
Symptoms of chronic renal failure in different stages
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