Henoch Schonlein purpura nephritis

Henoch Schonlein purpura nephritis

Henoch Schonlein purpura (HSP) is a kind of systemic vasculitis mediated by immune complex

Humoral immunity, but also involves cellular immunity, a number of cytokines and inflammatory mediators, coagulation mechanisms are involved in the pathogenesis of the disease.

Renal symptoms

1 rash: the onset and the main clinical manifestations of the disease, the occurrence of the distal limbs, buttocks and lower abdomen, symmetrical distribution, slightly higher than the skin

Skin surface, there may be itching, 1 ~ 2 weeks after the gradual decline, often can appear in batches. Less than 2 weeks from purpura to renal damage. 2 joint

Symptoms: it is a common symptom of the disease, characterized by multiple, non migratory, multi joint pain in the ankle joint. 3 gastrointestinal symptoms: often see

Mainly manifested as abdominal pain, abdominal discomfort and diarrhea. Common parts of the umbilicus and lower abdomen. Abdominal pain can sometimes be characterized by paroxysmal colic. Four

Other: lymphadenopathy, hepatosplenomegaly and nervous system involvement such as headache, seizures and abnormal behavior.

Renal manifestations

The main manifestations were abnormal urine, proteinuria and hematuria.

 

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