Treatment of Henoch Schonlein purpura nephritis in children

Treatment of Henoch Schonlein purpura nephritis in children

It is generally believed that the prognosis of this disease is better than that of the adult, and most of them can be recovered completely or only have slight abnormal urine. Clinically

Children with nephrotic syndrome (b) and nephritic syndrome, children with pathological grade III or above, often suffer from persistent renal damage and eventually lead to renal function

Incomplete. However, in recent years, Coup in children with Henoch Schonlein purpura nephritis after multi center study, that left a persistent kidney disease or nephritis in children with more

15% in the last 10 years, after the end of the year 20% in the last 20 years to the end of renal failure, should pay attention to.

anaphylatic purpura nephritis

anaphylatic purpura nephritis

1 general treatment of acute phase should rest in bed if there is a clear allergen, desensitization therapy should be. No clear allergen, should pay attention to whether there is no infection or latent infection

Can also be anti allergic treatment. Bleeding symptoms should be hematemesis hemostatic therapy intravenous drugs such as Simiti Martin (cemitidine (10mg/) kg.

D (omrprazolr), omeprazole or Losec; Losec) 0.3 to 0.5mg/ (kg times), 2 /d. There are edema can be applied hydrochlorothiazide, snails

Ester or diuretics like furosemide.

2 adrenal cortical hormone adrenocorticotropic hormone on abdominal pain curative effect is good, have certain effect to control bleeding rash and joint pain proteinuria

, but the effect of hematuria on allergic purpura is generally used in patients with large numbers of proteinuria in patients with Henoch Schonlein purpura nephritis

Adrenal cortical hormone therapy can significantly improve the prognosis. Can choose the dose of prednisone was 2mg/ (kg - D), a course of 1 to 2 weeks.

3 for immunosuppressive IV ~ VI allergic purpura nephritis, and the use of corticosteroids should be given cyclophosphamide (CTX) treatment

4 antiplatelet agents of long-term oral dipyridamole (dipyridamole, Pan Shengding, Persantin) 5 - 8mg/ (kg - D), 2 to 3 times a day orally

For the prevention and treatment of Henoch Schonlein purpura nephritis.

5 traditional Chinese medicine can be used for tripterygium glycosides tablets, suitable for I, II, III allergic purpura nephritis. Initial dose 2mg/ (kg * d), January

After the change to 1.5mg/ (kg * d), taking January, and finally to 1mg/ (kg / D) to maintain 1 ~ 2 months, allergic purpura nephritis has a good effect.

6 other people have reported the application of nifedipine (nifedipine, nifedipine) 0.25 ~ 0.5mg/ (kg times), 3 ~ 4 /d, can relieve allergic

Vascular lesion of Henoch Schonlein purpura nephritis. Vitamin E also has some therapeutic effect of IV ~ V patients can also try plasmapheresis and immunoadsorption, is expected to receive

Improvement of renal function. Dialysis and kidney transplantation for patients with renal failure.

 

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