The harm of high triglycerides

The harm of high triglycerides

The harm of high triglycerides 

The most direct embodiment the harm of high triglycerides in atherosclerosis. Blood triglyceride high consequence is easy to create a "thick", namely, high blood lipid levels in the blood viscous, in deposition on the walls of blood vessels, gradually form small plaque, which we usually said of atherosclerosis. And deposition of these patches on the walls of blood vessels, which will gradually expand the area and thickness of the vascular diameter smaller, hemorrheology, slow slow and accelerated the process of artery-clogging hemorrheology, serious when even interrupted blood flow. At this time, the harm of high triglycerides is quite serious. In addition to interrupt blood flow, and the fall off of obstruction can also cause blood clots; High triglycerides consequences no matter in which part, damage to the human body is very serious. If in the heart, can cause coronary heart disease, myocardial infarction; In the brain, can happen stroke, stroke; In fundus, can lead to decreased vision, blind; As in the kidney, can lead to kidney failure; Occurs in the lower extremities, body in poor blood flow lead to necrosis. 

In addition, the harm of high triglycerides also cause hypertension, gallstones, pancreatitis; Can also increase hepatitis, the male sexual dysfunction, lead to alzheimer's disease, etc. Studies have shown that high triglycerides consequences include a bit, it may lead to cancer. 

Triglycerides, abbreviations for tg, reference range: < 2.3 tendency for l (< 200 mg/dl). Normal triglyceride levels are influenced by living conditions, their inpidual differences and inpidual differences between larger than the total cholesterol, and increase along with the age increased. When tg > 4.5 tendency for l (> 400 mg/dl) can be diagnosed with high blood triglycerides.. 

Seen in the following diseases: 

(1) the family high tg blood disease, mixed hyperlipidemia. 

(2) secondary disease common in diabetes mellitus, glycogen storage disease, thyroid insufficiency, nephrotic syndrome, pregnancy, etc. 

(3) acute insulitis high-risk state, tg > tendency for 11.3 l (> 1000 mg/dl). Hypertension, cerebrovascular disease, coronary heart disease, diabetes, obesity and high lipoprotein hematic disease often have family gathering. Pure high tg levels, not an independent risk factor for coronary heart disease (CHD), only accompanied by high tc, LDL - c, low HDL - c is pathological significance. 

Triglyceride reduction can be found in the following diseases: 

Overactive thyroid, adrenal cortex hypofunction, severe liver function is low, easy to cause fatty liver disease, etc. 

Serum triglyceride level is mainly used to understand the status of the triglyceride metabolism in body, high blood triglycerides diagnosis and evaluation of risk of coronary heart disease, metabolic syndrome diagnosis and application of Friedewald formula calculating the level of LDL - C 4 aspects, such as the purpose. Friedewald formula LDL - C used in it have three prerequisites, the reliability of the results are also affected by triglyceride concentrations, as direct detection method of LDL - C gradually mature, the formula used less and less. 

Due to differences in race, diet, etc, classification level are also different from country to country. Such as the Netherlands think the ideal TG concentration is < 1.1 tendency for L, within the scope of the tendency of 1.1 ~ 4.0 L are at increased risk of coronary heart disease occurs, and > 4.0 tendency/L risk reduction, extremely elevated risk of pancreatitis highly increased. Turkey's research shows that TG moderately elevated (that is, the tendency of 1.6 ~ 2.5 L) are at increased risk of coronary heart disease. The pision of the current domestic standards for: appropriate TG level 1.69 or less tendency for L; > 1.69 tendency of elevated TG L. Ⅲ NCEP adult treatment panel 3rd report (ATP) serum TG can be pided into four levels: 5.64 or greater tendency for extremely high, L tendency for 2.26 / L ~ 5.63 tendency to rise, L tendency for 1.69 / L ~ 2.25 tendency for higher marginal, L < 1.69 tendency for L is normal. ATP Ⅲ thought lower TG treatment is more important than higher HDL - C, LDL and VLDL cholesterol and "is defined as the HDL cholesterol (TC - HDL - C)] as high TG group (2.26 or higher tendency for L) the second target of treatment. 

pre:Biochemistry of triglycerides
next:Determination of triglyceride

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