Membranous nephropathy proteinuria a lot but the prognosis i

Membranous nephropathy proteinuria a lot but the prognosis i

The following introduction is proteinuria may not be less than 1 g, but the prognosis can still be a good disease type-membranous nephropathy! 

Membranous nephropathy proteinuria a lot but the prognosis is very good!

Membranous nephropathy is a common type of nephropathy in middle and old people, usually occurring after 40 years of age. However, due to air pollution and environmental pollution in recent years, the incidence of membranous nephropathy is increasing and showing a trend of younger age. Not only middle and old age, but also more young people suffer from membranous nephropathy.

Membranous nephropathy is characterized by massive proteinuria: albuminuria is greater than 3.5 g / day. When some patients with membranous nephropathy have more proteinuria, they can even reach 20 g of protein per day.

Membranous nephropathy is pided into idiopathic membranous nephropathy and secondary membranous nephropathy according to the etiology. Such as exposure to nephrotoxic drugs and there are no underlying diseases; blood tests such as PLA2R antibody is positive; or kidney biopsy to determine which is the case.

In the case of secondary membranous nephropathy, the clinical focus is on etiological treatment: discontinuation of toxic drugs for induced diseases, or treatment for primary diseases, nephropathy usually improves.

The patient of membranous nephropathy, albuminuria is very prominent, many, and a lot of protein is the important factor that causes kidney failure, that is albuminuria does not turn negative, membranous nephropathy certainly can uremia? Studies have shown that even if membranous nephropathy is not completely alleviated, only partial remission is achieved, the prognosis will be significantly improved.

In patients with complete remission, the protein ration was less than 0.3 g / day, and the prognosis was very good, and few of them had renal failure, while those with partial remission had proteinuria of 0.3 ~ 3.5g / day, which was more than 50% less than the initial proteinuria, and the prognosis was also good. Most of the patients can maintain stable renal function for a long time, progress is very slow, but there is no remission, proteinuria is still more than 3.5 g / day, the prognosis is not good, with the passage of time, more and more patients have entered uremia.

And, there are studies that show that even if there is a lot of proteinuria at the start of the disease, if the proteinuria drops by more than 50 percent at one year, he will eventually get spontaneous remission after that. Maybe the proteinuria will always fall below 1 g. Still hovering around 1 g / 2 g, many patients are particularly anxious, but studies have shown that even if only partially relieved, the long-term prognosis of patients with membranous nephropathy is relatively good.

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