Summarize the five types of proteinuria
Normal urine containing trace amounts of protein, and urinary protein were negative in a regular examination. If laboratory tests positive urinary protein, the protein in the urine was more than the normal range, so the clinical proteinuria. The occurrence of proteinuria has the following five kinds of situations:
(1) glomerular proteinuria: whoever can cause all sorts of glomerular filtration membrane permeability increased glomerular disease, renal tubule and renal amyloidosis, diabetic nephropathy etc, all can promote the protein increase in glomerular filtrate, and more than the renal tubular reabsorption ability, therefore appeared mainly albumin proteinuria.
Tubular proteinuria (2) : due to the interstitial nephritis, analgesic nephropathy, chronic cadmium poisoning caused by renal tubular damage and various diseases such as metabolic defects, cause renal tubular function defects, although the number of protein glomerular filter out does not increase, but renal tubular reabsorption of protein, a decrease in the ability of the protein in his urine.
(3) overflow proteinuria: there is abnormal proteins in the blood, can through the glomerular filtration. Because of the excessive amount of overflow, renal tubular is not fully its absorption, creating a proteinuria.
(4) secretory proteinuria, renal tissue itself can secrete substances containing protein into the urine. Under normal circumstances, the renal tubules secrete a T - H protein, discharge of about 10 to 140 mg per day. In a variety of causes of proteinuria in the protein will increase. In addition, in normal urine contains a small amount of immunoglobulin, in renal tubular interstitial inflammation and tumors, including protein secretion will also enter the urine, caused by the reason of proteinuria, called secretory proteinuria.
(5) proteinuria: normal urine contains only very small amounts of soluble metabolites organization decomposition, belong to the small molecular weight proteins, these proteins can increase when sick.
Clinically seen proteinuria, mainly glomerular protein and renal tubular proteinuria, in specific cases, tend to have two or more of the protein.
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