Understand the treatment and prognosis of pyelonephritis

Understand the treatment and prognosis of pyelonephritis

Pyelonephritis (pyelonephritis) refers to inflammation of kidney Yu, mostly caused by bacterial infection, generally associated with urinary tract infection in clinic is not easy to distinguish. According to the clinical course of the disease and disease, acute and chronic pyelonephritis can be pided into two stages, chronic pyelonephritis is an important cause of chronic renal insufficiency.

1 general treatment to pay attention to personal hygiene, drinking plenty of water, not water, to avoid constipation.

2 etiology and treatment to remove complex and susceptible factors, such as surgery to remove the knot, stone, or correct reflux, etc..

3 symptomatic treatment to protect renal function, strengthen support therapy, enhance resistance, maintain water electrolyte balance, treatment of complications. Should emphasize the control of hypertension, blood pressure should be controlled at 17.3 / 10.7kPa (/ 80mmHg).

4 drug therapy

(1) treatment principle:

1) the bacteria are sensitive and less toxic, and have a high concentration of antibiotics in the renal parenchyma and urine.

2) a longer course of treatment (4 weeks or 6 weeks) in order to achieve the purpose of completely removing bacteria.

3 if you can not clear the bacteria and urinary tract infection repeated acute attacks, the use of low dose of a long course of antimicrobial therapy, at least 1 years of medication.

4, when uremia occurs, it is necessary to pay attention to the protection of renal function, to avoid accumulation of drug poisoning, but also can inhibit the growth of bacteria.

(2) the choice of drugs available: light cotrimoxazole, enzyme inhibitor or quinolones plus beta in semi synthetic broad-spectrum penicillin oral, severe combined drugs and intravenous medication, such as piperacillin tazobactam plus three (tazobactam) or imipenem Jiaxilasi Ding Na (imipenemcilastatinsodium) (the twenty-seventh chapter two use the same treatment acute pyelonephritis).

prognosis

Such as chronic pyelonephritis can be found in time and give proper treatment, the disease still not to develop into renal failure. Such as improper handling can occur in the late uremia.

 

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