How to prevent acute rejection after kidney transplantation?

How to prevent acute rejection after kidney transplantation?

Acute rejection is the most common type of rejection after transplantation. It is mainly cellular immunoreaction, which occurs within 6 days to 6 months after kidney transplantation, and the most frequently occurs in one week to two months after transplantation.

How to prevent acute rejection after kidney transplantation?

Clinical manifestations: fever, lack of urine, discomfort, joint pain, weight gain, elevated blood pressure, creatinine and urea nitrogen.

At present, because of the use of powerful immunosuppressive drugs such as cyclosporine A, mycophenolate mofetil and FK506, the clinical manifestations of acute rejection are no longer typical, so it is necessary to closely observe the condition of the disease. Joint pain should be timely reported to the doctor, in order to get timely diagnosis, timely treatment.

The causes of acute rejection were mainly due to the improper dose adjustment of immunosuppressants (CellCellulose, cyclosporine FK506), the insufficient dose of immunosuppressants caused by diarrhea, the reduction of immunosuppressant dosage, virus (herpes zoster) and bacterial infection. 

The number of acute rejection has an important effect on graft survival, so special attention should be paid to prevent the occurrence of acute rejection.

In order to prevent acute rejection, patients with high risk of renal transplantation and patients with poor matching (multiple recipients with moderate sensitization of HLA and recipients with poor HLA) were treated with sulfinil and zenepine before operation.

Take immunosuppressive drugs on time, do not arbitrarily reduce the dosage, to prevent randomness. The replacement of immunosuppressive drugs should be conducted under the guidance of the doctor, do not change casually. Patients with viruses, bacterial infections, diarrhea, Vomiting and other information should be promptly contact the transplant doctor in order to timely use of treatment and remedial measures. Regular detection of renal function and immunosuppressive drug concentration.

上一篇:What is the cause of recurrent chronic kidney disease and ho
下一篇:Children can also get kidney disease! These symptoms can't b

Hot News

Latest News

TCM Therapy

Chinese medicine treatment of pyelonephritis also have taboo

Chinese medicine treatment of pyelonephritis also have taboo

Pyelonephritis (pyelonephritis) refers to inflammat ...

Diet conditioning for nephropathy

Diet conditioning for nephropathy

Kidney disease is recognized as a chronic disease i ...

can kidney transplant cure Kidney disease?

can kidney transplant cure Kidney disease?

Myth.Hormones can cure the disease Many patients at ...

  Lupus nephritis patients do not come to menstruation

Lupus nephritis patients do not come to menstruation

Lupus erythematosus nephropathy is one of autoimmun ...

Tags

Leave a Message

看不清?点击更换

Contact