The study found that about 8% of the population, especially the elderly, had chronic renal dysfunction. Among these people, cardiovascular disease is common, and the incidence of coronary heart disease increases with the degree of renal dysfunction.
Chronic kidney disease with cardiovascular disease mortality rate is 10 to 30 times the general population. Early diagnosis and early treatment of chronic glomerulonephritis patients is very important. Therefore, for some typical cases, diagnosis should not wait more than one year, early identification is very important. Patients should be vigilant and found urine, abnormal blood pressure and edema should seek medical treatment promptly.
Chronic kidney disease patients, the traditional risk factors of coronary heart disease such as hypertension, hyperlipidemia, diabetes, smoking and other predictive significance. Moreover, the impact of hypertension in patients with chronic kidney disease may be more serious than the general population, coupled with the existence of these patients also increased homocysteine, oxidative stress, lipid metabolism disorders and inflammatory markers increased, and abnormal calcium and phosphorus metabolism, so that Vascular remodeling and compliance decreased, promote the formation of atherosclerosis.
Chronic kidney disease in patients with a higher incidence of cardiomyopathy. Hypertension and arteriosclerosis pressure overload, causing left ventricular concentric hypertrophy. In addition, anemia, fluid load and arteriovenous fistula caused by increased capacity load, leading to left ventricular hypertrophy. These abnormal structural changes in the heart, resulting in ventricular systolic and diastolic dysfunction, clinical manifestations of heart failure, myocardial ischemia. Especially dialysis patients, hypertension or hypotension caused by water-sodium retention and ultrafiltration, so that the diagnosis of heart failure is relatively difficult. Heart failure in dialysis patients is often a manifestation of severe cardiovascular disease and an independent risk factors for poor long-term prognosis.
Beijing In China