Normal daily filtration of raw urine up to 180 liters, but after renal tubular reabsorption, secretion, the final concentration of only about 1.5 liters of excretion. Which contains about 40 to 100 mg protein, urine protein qualitative method is not measured.
Proteinuria is not all pathological, functional proteinuria and pathological proteinuria. Functional proteinuria, also known as physiological proteinuria, refers to the temporary presence of proteinuria in healthy people. More common in young people, in the strenuous exercise, fever, fever, cold, mental stress and other factors, renal vasospasm or congestion, leading to increased glomerular filtration membrane permeability and a large number of protein "slip through the net."
Urine protein in normal pregnant women can be mildly increased, which increased with the position and renal flow, increased glomerular filtration rate. Functional proteinuria proteinuria will disappear after the cause is released. It is also known as reversible proteinuria or transient proteinuria.
There is no protein in urine, with the amount of protein, there is a simple and crude test method: the urine boil, the urine can appear white turbid, add 5% acetic acid 5 to 10 drops and then boil, such as turbidity disappear, Indicating no protein in urine, urine protein qualitative test negative; such as turbidity does not disappear but increased, was flocculent precipitate or clot, urine protein qualitative test was positive.
Pathological proteinuria refers to the body of a system or organ disease caused by persistent urine protein. Urinary protein in general 24 hours more than 150 mg. Common in three situations:
Glomerular proteinuria: glomerular capillary wall damage (such as immune damage) caused by a variety of reasons, to reduce the load or loss, resulting in increased glomerular permeability. More plasma protein filtration, beyond the renal tubular reabsorption, resulting in proteinuria. Such as acute and chronic nephritis, lupus nephropathy, diabetic nephropathy.
Renal tubular proteinuria: tubular lesion or renal tubular defects, reduced protein reabsorption or increased secretion of protein, resulting in increased urine protein. Such as renal tubular acidosis, nephropathy caused by analgesics, antibiotic nephrotoxicity performance.
Urine overflowing proteinuria (also known as coagulation proteinuria) urine turbid when heated to 40 ℃, 60 ℃ when the coagulation, up to 100 ℃ when dissolved. See multiple myeloma, primary amyloidosis, macroglobulinemia and so on.
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